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Buy Ephedrine is an interesting medication with a wide variety of applications, including: Buy Ephedrine crystal powder Hcl online
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ephedrine, derived from plants in the Ephedra genus, has been used in traditional Chinese medicine for over 5000 years, and continues to see wide-spread use today.
Use of the medication in other countries is varied. Though once widely available without a prescription, it is now regulated in most parts of the world, either requiring a prescription, sold only in limited dosage strength or quantities, or banned altogether. In most cases such regulations are an attempt to limit availability of ingredients used in the manufacture of drugs such as methamphetamine. Clients who buy ephedrine from Kiwi Drug are responsible for complying with local laws or regulations regarding purchase, use and possession. Buy Ephedrine crystal powder Hcl online
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The ideal dose and frequency of administration for this medication depends, obviously, on the condition being treated and the health of the patient. Too much Ephedrine can produce life-threatening side effects, though smaller doses are generally considered safe for healthy adults.
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- Most countries which have some restrictions on consider 8 to 12.5 mg to be safe, so much so that it is often available without a prescription in many areas.
- For many conditions, including asthma, COPD and hypotension, 25 to 50 mg are taken every 3 or 4 hours, up to 150 mg in a 24 hour period.
- Taking more than 150 mg a day, or taking 150 mg or more all at once, is generally considered risky.
- Taking 400 mg or more is very likely to cause dangerous side effects, particularly heart problems. can be life-threatening even at considerably smaller doses in those with preexisting conditions. Buy Ephedrine crystal powder Hcl online
Tablets may be taken with or without food. Taking with food may ease nausea if it occurs. Ephedrine may increase urine production; drink plenty of fluids to prevent dehydration.
The medication may be taken regularly for several weeks or months, such as when treating hypotension, or it may be taken sporadically as-needed, such as when treating an asthma attack or as a decongestant. Buy Ephedrine crystal powder Hcl
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The most common side effects associated with proper Ephedrine use are mild and similar to those encountered with caffeine or other stimulants:
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Ephedrine should not be used without explicit doctor approval in cases where there is any pre-existing condition or major medical issue. It should not be used by women who are pregnant or breast feeding. Patients at particular risk of serious side effects include those suffering from hypertension (high blood pressure), diabetes, cardiovascular disease and prostrate issues. Buy Ephedrine crystal powder Hcl
The medication may interact with a wide range of other drugs, including recreational drugs and supplements. Use with extreme caution when taking other stimulants. Check with a doctor or the insert included with the medication for a full list of possible interactions. Buy Ephedrine crystal powder Hcl online
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As mentioned previously, some areas restrict the sale, possession and use of this medication. It’s a good idea to check local regulations before you buy; a prescription does not necessarily mean it’s legal to purchase from any source or in any dosage strength. Buy Ephedrine crystal powder
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Ephedrine is a medication and stimulant. It is often used to prevent low blood pressure during spinal anesthesia. It has also been used for asthma, narcolepsy, and obesity but is not the preferred treatment. It is of unclear benefit in nasal congestion. It can be taken by mouth or by injection into a muscle, vein, or just under the skin. Onset with intravenous use is fast, while injection into a muscle can take 20 minutes, and by mouth can take an hour for effect. When given by injection it lasts about an hour and when taken by mouth it can last up to four hours.
Common side effects include trouble sleeping, anxiety, headache, hallucinations, high blood pressure, fast heart rate, loss of appetite, and inability to urinate. Serious side effects include stroke, heart attack, and abuse. While likely safe in pregnancy, its use in this population is poorly studied. Use during breastfeeding is not recommended. Ephedrine works by increasing the activity of the α and β adrenergic receptors
Ephedrine was first isolated in 1885. It is on the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system. It is available as a generic medication. The wholesale cost in the developing world is about US$0.69–1.35 per dose. In the United States, it is not very expensive. It can normally be found in plants of the Ephedra type. Dietary supplements that contain ephedrine are illegal in the United States.
An exception is when used in traditional Chinese medicine.
Ephedrine is a sympathomimetic amine and substituted amphetamine. It is similar in molecular structure to phenylpropanolamine, methamphetamine, and epinephrine (adrenaline). Chemically, it is an alkaloid with a phenethylamine skeleton found in various plants in the genus Ephedra (family Ephedraceae). It works mainly by increasing the activity of norepinephrine (noradrenaline) on adrenergic receptors. It is most usually marketed as the hydrochloride or sulfate salt.
Ephedrine exhibits optical isomerism and has two chiral centers, giving rise to four stereoisomers. By convention, the pair of enantiomers with the stereochemistry (1R,2S) and (1S,2R) is designated ephedrine, while the pair of enantiomers with the stereochemistry (1R,2R) and (1S,2S) is called pseudoephedrine. Ephedrine is a substituted amphetamine and a structural methamphetamine analog. It differs from methamphetamine only by the presence of a hydroxyl group (—OH).
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The isomer which is marketed is (−)-(1R,2S)-ephedrine.
Ephedrine hydrochloride has a melting point of 187−188 °C.
In the outdated D/L system (+)-ephedrine is also referred to as L-ephedrine and (−)-ephedrine as D-ephedrine (in the Fisher projection, then the phenyl ring is drawn at the bottom).
Often, the D/L system (with small caps) and the d/l system (with lower-case) are confused. The result is that the levorotatory l-ephedrine is wrongly named L-ephedrine and the dextrorotary d-pseudoephedrine (the diastereomer) wrongly D-pseudoephedrine.
The IUPAC names of the two enantiomers are (1R,2S)- respectively (1S,2R)-2-methylamino-1-phenylpropan-1-ol. A synonym is erythro-ephedrine
Ephedrine Sulphate (1932), Ephedrine Compound (1932), and Swan-Myers Ephedrine Inhalant No. 66 (circa 1940)
Both ephedrine and pseudoephedrine increase blood pressure and act as bronchodilators, with pseudoephedrine having considerably less effect.
Ephedrine may decrease motion sickness, but it has mainly been used to decrease the sedating effects of other medications used for motion sickness.
Ephedrine promotes modest short-term weight loss, specifically fat loss, but its long-term effects are unknown. In mice, ephedrine is known to stimulate thermogenesis in the brown adipose tissue, but because adult humans have only small amounts of brown fat, thermogenesis is assumed to take place mostly in the skeletal muscle. Ephedrine also decreases gastric emptying. Methylxanthines such as caffeine and theophylline have a synergistic effect with ephedrine with respect to weight loss. This led to the creation and marketing of compound products. One of them, known as the ECA stack, contains ephedrine with caffeine and aspirin. It is a popular supplement taken by bodybuilders seeking to cut body fat before a competition.
As a phenethylamine, ephedrine has a similar chemical structure to amphetamines and is a methamphetamine analog having the methamphetamine structure with a hydroxyl group at the β position. Because of ephedrine’s structural similarity to methamphetamine, it can be used to create methamphetamine using chemical reduction in which ephedrine hydroxyl group is removed; this has made ephedrine a highly sought-after chemical precursor in the illicit manufacture of methamphetamine. The most popular method for reducing ephedrine to methamphetamine is similar to the Birch reduction, in that it uses anhydrous ammonia and lithium metal in the reaction. The second-most popular method uses red phosphorus, iodine, and ephedrine in the reaction.
Through oxidation, ephedrine can be easily synthesized into methcathinone. Ephedrine is listed as a table-I precursor under the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances.
Detection of use
Ephedrine may be quantified in blood, plasma, or urine to monitor possible abuse by athletes, confirm a diagnosis of poisoning, or assist in a medicolegal death investigation. Many commercial immunoassay screening tests directed at the amphetamines cross-react appreciably with ephedrine, but chromatographic techniques can easily distinguish ephedrine from other phenethylamine derivatives. Blood or plasma ephedrine concentrations are typically in the 20-200 µg/l range in persons taking the drug therapeutically, 300-3000 µg/l in abusers or poisoned patients and 3–20 mg/l in cases of acute fatal overdose. The current WADA limit for ephedrine in an athlete’s urine is 10 µg/ml.